These are generally performed in a sterile “clean” room. You will have a combination of anaesthetic and antiseptic drops instilled in the eye in order to make the procedure as comfortable as possible and to minimise the risk of infection. The eye will be covered and a small sterile speculum used to keep your eyelids apart. A small volume of an antiVEGFsolution such as Lucentis, Eylea or Avastin, all of which are effective in DMO, is then administered into the eye using a tiny needle. This part of the procedure lasts only a few seconds, with the entire procedure lasting just over 5 minutes. Most patients report minimal discomfort from the injection. The eye is then cleaned and you go home. It is normal to experience some watering and redness for 24-48 hours after the procedure. It is common also to experience some floaters in the eye which also improve over a few days. Risks arerare, but do include less than 1 in 1000 risk of a blinding infection in that eye, a small risk of bleeding in the eye, and a slightly higher change of developing a complication during cataract surgery whenever that is required.